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Dipana

Therapeutic category: Hepatoprotector and Immunomodulator.

Composition:
Each coated tablet contains the following dried aqueous extracts:

Picorrhiza Kurroa 80 mg
Andrographis paniculata 40 mg
Eclipta alba 40 mg
Phyllanthus niruri 40 mg
Solanum nigrum 30 mg
Tinospora cordifolia 30 mg
Bacopa monnieri 10 mg
Boerhaavia diffusa 10 mg
Zingiber officinale 10 mg
Piper longum 8 mg

Pharmacological action:

Dipana has hepato-protective, choleretic and immunomodulatory actions.
Dipana prevents liver injury by toxic substances (alcohol, drug preparations etc.) preserving liver's cellular texture by restoring glutathione level. It decreases the number of free radicals due to its antioxidant effect and also has membrane stabilizing activity. By increasing the flow of bile it helps in the early excretion of toxic substances from the liver. Dipana promotes restoration of liver cells` structure and functions, normalizes composition of bile and its flow, and inhibits connective tissue formation in liver.
Dipana has an immunomodulating activity influencing the innate components of immune system, accelerates recovery from illnesses.
Dipana improves the condition of patients with liver diseases, improves cognitive function in patients with liver diseases.

Indications
Dipana is used for the treatment (including as a part of combination therapy) of the following diseases:

  1. Acute and chronic hepatitis including viral hepatitis
  2. Alcoholic liver diseases
  3. Liver steatosis of various etiology
  4. Cirrhosis
  5. Toxic liver injury (due to the administration of anti-tubercular, anti-diabetes, anti-arthritis drugs and antibiotics with known hepato-toxic effects).
  6. Dyskinesia of bile passages including the pain syndrome after cholecystectomy (cystectomy)
  7. Prophylaxis of gall stone formation.
  8. For patients exposed to radiation, radiotherapy and chemotherapy
  9. During rehabilitation period after operations and long-term diseases to normalize the immune status
  10. For children with low appetite and weight caused by various disorders
  11. Non-Alcoholic fatty liver disease.

Dosage:
Adults: 2-3 tablets, 2-3 times a day as directed by the physician

Children: Children older than 10 years 1 tablet twice a day.
Dipana tablets should be taken before food or drinks with sufficient amount of water.

Contraindications
Individual intolerance to any of the preparation's components.

Adverse effects
Allergic reactions are possible.
One may experience the following transient phenomena: dryness of mouth, nausea, enterospasms, diarrhea, sleep disturbances, cephalalgia, and diuresis increase. With continuation of treatment these symptoms pass off.

Warnings and Precautions
During the treatment adequate intake of fluids is recommended.
In pregnant, breast feeding women and children less than 10 years of age consult physician before use.

Presentation

  • 12 tablets are packed in a blister and four such blisters are packed in a unit carton along with package insert.
  • 90 tablets are packed in a green coloured, labeled HDPE jar, along with a silica gel bag, Free space in the bottle is filled with hygroscopic cotton. The jar is sealed with foil printed’ Dipana’ and fitted with a dark green colour cap. The jar is in a unit carton along with package insert.

Storage
Store at or below 25°C in a dry place, protected from light.
Keep it out of children’s reach.